52 research outputs found

    Convergence Rates in L^2 for Elliptic Homogenization Problems

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    We study rates of convergence of solutions in L^2 and H^{1/2} for a family of elliptic systems {L_\epsilon} with rapidly oscillating oscillating coefficients in Lipschitz domains with Dirichlet or Neumann boundary conditions. As a consequence, we obtain convergence rates for Dirichlet, Neumann, and Steklov eigenvalues of {L_\epsilon}. Most of our results, which rely on the recently established uniform estimates for the L^2 Dirichlet and Neumann problems in \cite{12,13}, are new even for smooth domains.Comment: 25 page

    Game Based Learning on Urban Sustainability: The "Sustain" Project

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    SUSTAIN is an ERASMUS+ project with an innovative perspective on urban sustainability. Its target is to promote the importance of sustainability on the everyday problems of the cities among the students of higher education, which are the policy makers of tomorrow and the ones that will shape the future. In order to achieve its goals, the research team will develop a course that will be based on an interactive game with an analytical style of education. This game will allow students to learn about transportation sustainability and societal metabolism through playing. In addition, the research team will develop small and illustrative simulation models, which will make the definitions more concrete and allow students to experiment in a consequence-free environment. It is a quite innovative and hybrid perspective way of learning, in the sense that it will combine game-based learning with a cognitive and analytical style of education

    Rezultate partiale într-o cultură de busuioc în sistem de intercropping

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    The paper presents the behavior of basil (Ocimum basilicum L.) crop in two intercropping systems with runner bean (Phaseolus coccineus L.) and cherry tomatoes (Licopersicon esculentum L.). The obtained results were evaluated based on morphological and phenological characteristics of the chosen species, revealing the agrophitotechnological character of alimentary basil and its productivity in the two intercropping systems. Due to the decorative valences that basil presents, which were highlighted in the intercropping systems, this species brings unity and harmony to the specific ornamental vegetable garden of our country

    Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group.

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    Cancer immunotherapy has transformed the treatment of cancer. However, increasing use of immune-based therapies, including the widely used class of agents known as immune checkpoint inhibitors, has exposed a discrete group of immune-related adverse events (irAEs). Many of these are driven by the same immunologic mechanisms responsible for the drugs\u27 therapeutic effects, namely blockade of inhibitory mechanisms that suppress the immune system and protect body tissues from an unconstrained acute or chronic immune response. Skin, gut, endocrine, lung and musculoskeletal irAEs are relatively common, whereas cardiovascular, hematologic, renal, neurologic and ophthalmologic irAEs occur much less frequently. The majority of irAEs are mild to moderate in severity; however, serious and occasionally life-threatening irAEs are reported in the literature, and treatment-related deaths occur in up to 2% of patients, varying by ICI. Immunotherapy-related irAEs typically have a delayed onset and prolonged duration compared to adverse events from chemotherapy, and effective management depends on early recognition and prompt intervention with immune suppression and/or immunomodulatory strategies. There is an urgent need for multidisciplinary guidance reflecting broad-based perspectives on how to recognize, report and manage organ-specific toxicities until evidence-based data are available to inform clinical decision-making. The Society for Immunotherapy of Cancer (SITC) established a multidisciplinary Toxicity Management Working Group, which met for a full-day workshop to develop recommendations to standardize management of irAEs. Here we present their consensus recommendations on managing toxicities associated with immune checkpoint inhibitor therapy

    Regional development gaps in Argentina: A multidimensional approach to identify the location of policy priorities

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    Spatial inequalities within Latin American countries have historically attracted the interest ofacademics, policy-makers, and international agencies. This article aims to provide amultidimensional diagnosis of provincial development gaps in Argentina, in order to identifythe location of policy priorities. Therefore, we built a large database, which covers sevendevelopment dimensions, and applied multivariate analysis techniques to overcome someanalytical limitations of previous studies. Results show the stability of provincial developmentgaps between 2003 and 2013 and some heterogeneity within geographic regions. Instead,cluster analysis offers a better classification of Argentine provinces according to theirdevelopment gaps, which can help the government to prioritize the places wheredevelopment policies are strategic.Fil: Niembro, Andrés Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte; Argentina. Universidad Nacional de Río Negro; ArgentinaFil: Sarmiento, Jesica Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte; Argentina. Universidad Nacional de Río Negro; Argentin

    Studii de caz referitoare la folosirea design-ului peisager în cultura legumelor

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    The paper presents an analysis of Romanian household vegetable gardens, based on ornamental criteria and specific vegetable growing technologies characteristic to these plant displays in cultivation. The weak and strong points of the studied vegetable gardens were marked out through a SWOT analysis and based on it solutions were elaborated to improve them on an aesthetic, technologic and workable level in accordance with specialized literature. The obtained results offered unity, balance and an increasing aesthetic value to the plant display, participating in an active mater to the enlargement of their sustainability degree
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